Keratocystic odontogenic tumor has some very distinctive findings that are easily recognized. A rare case report suchetabansal 1 andsanjeevkumarjoshi 2 department of oral and maxillofacial. It has been confused with other pathologic entities such as ameloblastomas, carcinomas, and fibromas and clinically may resemble localized periodontal disease. Squamous odontogenic tumor is a rare odontogenic tumor, since until today no more than 110 cases have been described and confirmed 5, 6, 8,9,12,14. The tumor is often asymptomatic, although it can present with symptoms of pain and tooth mobility. Tumors located in the anterior region of the mandible are uncommon. Squamous odontogenic tumor is a distinct entity separate from the more.
We are presenting the twentysecond case to be reported in the literature and only the fifth case with multiple quadrant lesions. Excluding those squamous odontogenic tumor like proliferations described as being within the walls of odontogenic cysts and the isolated nonreactive squamous odontogenic proliferations or soft tissue lesions,9 fifteen additional cases have been reported in the literature. Jan 01, 2021 squamous odontogenic tumor sot is a rare, benign, locally infiltrative odontogenic tumor of the gnathic bones. In many cases their relationship to the teeth is fairly clearcut, both histologically and radiographically. This is the first description of reconstruction with autologous and homologous bone grafts of a discontinuity defect of the mandible resulting from en. Sots generally occur in adults, but have a wide age range with cases reported from childhood to the. Background primary intraosseous squamous cell carcinoma pioscc is a rare malignant tumour that arises within the jaws and derives from odontogenic epithelial remnants. Squamous odontogenic tumor sot is a rare, benign, locally infiltrative odontogenic tumor of the gnathic bones. Squamous odontogenic tumor with unusual localization and. Squamous cell carcinoma scc derived from keratocystic odontogenic tumor is an extremely rare tumor that is limited to the jaws.
Peripheral squamous odontogenic tumour institute of. Differential diagnosis, non odontogenic lesions, odontogenic lesions, radiographic aspects, squamous odontogenic tumor. The vast majority of these tumors are benign or locally aggressive with few malignant variants being reported. Squamous odontogenic tumor is a very rare benign tumor that arises from remnants of the dental lamina and occurs equally in the mandible and maxilla. Squamous odontogenic tumor like proliferations in radicular cysts. It is composed of islands of bland, welldifferentiated squamous epithelium of varying shape and size. Furthermore, the appearance of such malignancy in an odontogenic tumor such as keratocystic odontogenic tumor is. A patient with squamous cell carcinoma arising from an odontogenic keratocyst is studied clinically, radiographically, and pathologically. Squamous odontogenic tumor a benign epithelial odontogenic tumor comprised of oval islands of squamous epithelium showing no ameloblastic features well circumscribed radiolucency a familial form with multifocal lesions may be seen root divergence is common tx. Squamous odontogenic tumor sot is a rare benign neoplasm with odontogenic epithelium origin.
Figure 2 from squamous odontogenic tumorlike proliferations. Squamous odontogenic tumour is a rare, benign epithelial odontogenic neoplasm. Although potentially locally destructive, okc is a benign odontogenic process that typically presents with clinical and radiographic features characteristic of a benign intraosseous neoplasm. We are presenting the twentysecond case to be reported in the literature and only the fifth.
Squamous odontogenic tumor radiology reference article. The patient who was documented to have an odontogenic keratocyst, 1 year later had a squamous carcinoma removed from the recurrent cyst. The clinical, radiographic, histologic and some immunohistochemical findings in a case of squamous odontogenic tumor sot in a 56yr. Keratinocystic odontogenic tumor odontogenic keratocyst keratinocystic odontogenic tumor three important things associated with this diagnosis.
The squamous odontogenic tumor is a rare, benign epithelial odontogenic neoplasm first described by pullon et al. It is a slow and progressively growing lesion that invades the trabe. Most intraosseous carcinomas originate from the epithelial lining of odontogenic cysts, so they. Who classification benign odontogenic epithelium without odontogenic ectomesenchyme ameloblastoma squamous odontogenic tumor pindborgs tumor clear cell odontogenic tumor odontogenic epithelium with odontogenic ectomesenchyme with or without dental hard tissue formation. This type of tumor was first described by pullon et al. An updated analysis of 170 cases reported in the literature. Despite the bone involvement and benign nature of sot, this tumor. Since then, there have been less than 50 reported cases. Squamous odontogenic tumor sot is a benign odontogenic tumor classified according to the world health organization who in 2005 as an epithelium odontogenic tumor with around 50 cases reported in the englishlanguage literature at this time 1 barnes l, everson jw, reichart p, sidransky d, eds. Squamous odontogenic tumour sot is a rare, benign epithelial tumour of odontogenic origin. The squamous epithelial lining of this cystic tumor demonstrates an. Jun 01, 1986 squamous odontogenic tumor is a rare, benign, odontogenic lesion.
Discussion benign odontogenic tumors include the wellknown entities like ameloblastomas, squamous odontogenic tumours, calcifying epithelial odontogenic tumor and adenomatoid odontogenic tumor. Primary intraosseous squamous cell carcinoma arising from an. Squamous odontogenic tumor of maxilla a rare case report. Patients may present with an increase in the volume of the maxillae or mandible, tooth mobility, ulceration of the soft tissue, painful symptoms, and tooth displacement.
Squamous odontogenic tumor and squamous odontogenic tumor. The squamous odontogenic tumor sot is a rare, benign, locally infiltrative neoplasm of the jaws that appears to originate from the rests of. Squamous cell carcinoma arising from a keratocystic. Squamous odontogenic tumor europe pmc article europe.
Peripheral squamous odontogenic tumor malathi n, radhika t. A novel and completely revised who classification from 2005, which encompasses the histopathological and genetic criteria of sots, describes a group of epithelial odontogenic tumors that comprises the ameloblastoma. First described in the 20 th century by pullon in 1975 2 in his case series of 6 cases, it is a rare entity in which both. Amyloidproducing odontogenic tumor apot, an epithelial odontogenic tumor, is a rare and poorly understood oral neoplasm in animals. In 1992, such classification was titled odontogenic tumors, but still included odontogenic cysts and allied lesions. Histologic examination of the biopsy material resulted in a diagnosis of squamous odontogenic tumor a rare, benign epithelial odontogenic neoplasm. World health organization classification of tumors pathology and genetics of. The tumor originates in the gingival rests of malassez, remnants of dental lamina or gingival surface epithelium. Squamous cell carcinoma scc arising within the lining of an odontogenic keratocyst okc is a rare occurrence.
Sots generally occur in adults, but have a wide age range with cases reported from childhood to the eighth decade. Squamous odontogenic tumor reichart 1990 journal of. Odontogenic keratocyst because of its behavior, many oral pathologists now consider the okc an odontogenic tumor that has a cystic form 2005 classi. Squamous odontogenic tumor sot is a locally infiltrative neoplasm consisting of islands of welldifferentiated squamous epithelium in a fibrous stroma 1. Review of the literature and a new case volume 99 issue 9. Squamous odontogenic tumor is a rare, benign epithelial odontogenic neoplasm. Squamous odontogenic tumour is a benign odontogenic tumour composed of a welldifferentiated squamous epithelium immersed in a fibrous connective tissue. A recurrent case of sot with peripheral occurrence is described. Epidemiology they generally occur in adults, but have a wide age range with cases reported from childhood to the 8th decade pathology it is considered to represent. The squamous odontogenic tumour is a rare benign neoplasm whose aetiology remains. Squamous odontogenic tumor exceedingly rare neoplasm. Parulis buccal or lingual odontogenic source of infection nonvitall tooth periapical radiolucency purulent exudate gutta purcharadiographic tracer.
Pdf squamous odontogenic tumor manuel davila academia. Furthermore, the appearance of such malignancy in an odontogenic tumor such as keratocystic odontogenic tumor is considered extremely rare. Squamous odontogenic tumor hamartomatous proliferation maxillary incisorcanine and mandibular molar tooth mobility common complaint radiology triangular, localized radiolucency between contiguous teeth histology oval nest of squamous epithelium in mature collagen stroma treatment extraction of involved tooth and. Most intraosseous carcinomas originate from the epithelial lining of odontogenic cysts, so they are called odontogenic carcinomas. Despite the bone involvement and benign nature of sot, this tumor can infiltrate adjacent soft. One such neoplasm, the squamous odontogenic tumor sot originally described 20 years ago is now a well. Consequently, the source of epithelial lining of odontogenic cysts could be considered as the indirect origin of sotlps. It most often affects the posterior mandible and most commonly presents in the third decade of life. Although notch receptors and ligands have been shown to play a role in cell fate decisions in ameloblastomas, the role of these cell. Apr 08, 2010 background squamous odontogenic tumor sot is a rare benign odontogenic epithelial neoplasm. Primary intraosseous squamous cell carcinoma arising from. Liselott lindh, dds, phd, faculty of odontology, malmo university, malmo, sweden. We report a case of sot occurring in a 26yearold female in the anterior mandible with. The clinical presentation is mostly asymptomatic, though pain and tooth.
Squamous odontogenic tumor is a rare tumor that supposedly develops from the remnants of dental lamina, or of the cell rests of malassez rom, or gingival epithelium 1. Squamous odontogenic tumors are rare neoplasms of the jaw that are benign and locally infiltrative. Squamous odontogenic tumor is a rare, benign, odontogenic lesion. Squamous odontogenic tumor sot is a benign odonto genic tumor classified according to the world health organization who in 2005 as an epithelium odontogenic tumor with around 50 cases reported in the englishlanguage literature at this time. Jul 15, 2014 squamous odontogenic tumors are rare neoplasms of the jaw that are benign and locally infiltrative. Squamous odontogenic tumor sot is a benign odontogenic tumor classified according to the world health organization who in 2005 as an. Although primary intraosseous squamous cell carcinoma pioscc aris ing from odontogenic cysts has been reported occasion ally, studies investigating the clinicopathologic features. In other words, odontogenic tumors arise from odontogenic tissues.
Distinguishing squamous odontogenic tumor like proliferations sotlps is important in odontogenic cysts to avoid misinterpretation such as a squamous odontogenic tumor, welldifferentiated squamous cell carcinoma, and acanthomatous type of ameloblastoma. Squamous odontogenic tumor like proliferation in a radicular cyst discussion squamous odontogenic tumor sot is an infrequent, benign maxillary neoplasm originating from the epithelial rests of malassez of the periodontal ligament. They occur more frequently in men and the mean age of patients is 57 years. Squamous cell carcinoma arising from an odontogenic. The 1971 who classification contained odontogenic tumors, odontogenic cysts and allied lesions. Squamous odontogenic tumors sots are benign, locally infiltrative neoplasms that localize to the periodontium. Case report squamous odontogenic tumor with unusual. Peripheral odontogenic tumors squamous cell carcinoma expansile central bone tumors. Sot is a very rare entity, found in any area of the alveolar bone.
Squamous odontogenic tumor and squamous odontogenic tumor like proliferations in odontogenic cysts. An odontogenic keratocyst is a rare and benign but locally aggressive developmental cyst. Histopathologically, sot can be easily misdiagnosed as an acanthomatous ameloblastoma. The squamous odontogenic tumor sot is a rare, benign, locally infiltrative neoplasm of the jaws that appears to originate from the rests of malassez. Squamous odontogenic tumour of anterior mandible a. Diagnosing the most common odontogenic cystic and osseous. An odontogenic tumor is a neoplasm of the cells or tissues that initiate odontogenic processes examples include. Intraosseous squamous cell carcinoma arising in association with a squamous odontogenic tumour of the mandible. This is a pdf file of an unedited manuscript that has been accepted for publication. Squamous odontogenic tumor and squamous odontogenic. A slowgrowing painless expansive swelling is the common presenting symptom.
Ameloblastic fibroma this is a tumor of childhood, the typical patient is about 12 14 years old, seldom is it seen beyond age 20. Squamous cell carcinoma arising within a maxillary. Because of histologic overlap, sot has often been overdiagnosed as ameloblastoma and squamous cell carcinoma. Squamous cell carcinoma arising in recurrent odontogenic. A case report mervet moussa, marwa mokbel elshafei abstract introduction. This study is aimed at reporting 4 cases of these clinicopathological proliferations in order to shed more light on the importance of. This tumor histopathologically is described as the proliferation of welldi. Squamous odontogenic tumor oral surgery, oral medicine, oral. In other cases, their relationship to teeth clinical pathology. The clinical, radiographic and morphologic features of the squamous odontogenic tumor are discussed. World health organization classification of tumors pathology and genetics of head. Sot appears to be of benign nature, most probably originating from the epithelial rests of malassez. Squamous odontogenic tumour radiology reference article. Squamous odontogenic tumor is a rare benign neoplasm and may affect multiple sites in the mouth.
A primary intraosseous squamous cell carcinoma pioscc is defined as a squamous cell carcinoma arising within the jaw bones, which has no initial connection with the oral mucous membrane and develops from remnants of odontogenic epithelium deriving embryologically from ledge or epithelial cell rest of malassez 2. This proliferation of mature squamous epithelium may arise from the rests of malassez or other residual odontogenic rests 24. Squamous cell carcinoma arising from the lining of an odontogenic cyst is one important rare subcategory of such lesions with an incidence of 0. Sot growth is slowgradual, but it might invade the trabecular bone and in.
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